Benzenemethanol, α-(chloromethyl)-4-fluoro-, (αR)

Benzenemethanol, α-(chloromethyl)-4-fluoro-, (αR) - Names and Identifiers

Name	(R)-2-Chloro-1-(4-fluorophenyl)ethanol
Synonyms	(R)-2-CHLORO-1-(4-FLUOROPHENYL)ETHANOL (R)-2-Chloro-1-(4-fluorophenyl)ethanol (1R)-2-Chloro-1-(4-Fluorophenyl)ethanol (R)-2-Chloro-1-(4-fluorophenyl)ethan-1-ol [R]-1-chloro-2-(4-fluorophenyl)-2-ethanol Benzenemethanol, α-(chloromethyl)-4-fluoro-, (αR) Benzenemethanol, α-(chloromethyl)-4-fluoro-, (αR)-
CAS	126534-43-8

Benzenemethanol, α-(chloromethyl)-4-fluoro-, (αR) - Physico-chemical Properties

Molecular Formula	C8H8ClFO
Molar Mass	174.6
Density	1.282±0.06 g/cm3(Predicted)
Boling Point	256.6±25.0 °C(Predicted)
pKa	13.14±0.20(Predicted)
Storage Condition	2-8°C

Benzenemethanol, α-(chloromethyl)-4-fluoro-, (αR) - Introduction

(R)-2-chroo-1-(4-fluorophenyl)ethanol is an organic compound with the chemical formula C8H8ClFO. It is a chiral molecule with one chiral center, so there are two enantiomers (R) and (S).

The compound has a colorless to pale yellow solid with a benzene-like aroma. It has low solubility, almost insoluble in water, soluble in organic solvents such as chloroform and ether.

(R)-2-choro-1-(4-fluorophenyl)ethanol has some applications in the pharmaceutical and agrochemical fields. It is used as a synthetic intermediate for the preparation of some bioactive compounds, such as anticancer drugs, insecticides and fungicides. In addition, it can also be used as a lead compound for chiral catalysts.

The compound can be synthesized by a variety of methods, such as by Chiral separation of 2-chloro-1-(4-fluorophenyl) ethanol, alternatively, the asymmetric synthesis is carried out by using a chiral catalyst under appropriate conditions.

Last Update：2024-04-09 20:52:54